Depending on the cause of the hang, this shortcut might help or not. If it is due to a graphics driver, restarting them without rebooting the machine will work.
But if that doesn't work, try using Alt + Tab to switch to another software. If that doesn't work, try Ctrl + Shift + Esc to open Task Manager and stop the pending application.
When all of the above methods don't work, try Ctrl + Alt + Del. If after a while Windows still does not respond, you only have to force the shutdown by holding down the Power button , this is like unplugging power and the last solution when the system hangs.
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