Over-active bladder medication has been linked to depression

A new finding suggests that the drug used to treat bladder syndrome overreacts to the risk of developing depression in women within three years.

Previously, overactive bladder has affected 16% of adults in the United States and the incidence has increased with age - Information from the US National Center for Biotechnology Information said.

Anti-emetic drugs are often used to treat overactive bladder because they are able to block muscarinic receptors and prevent contractions outside the bladder caused by intermediate acetylcholine.

The researchers analyzed Taiwan's longitudinal baseline health insurance data and identified 1,952 women with overactive bladder who received antimuscarinics and 9760 supplements. women also get the same disease but do not take antimuscarinics and monitor these two groups for three years. 

The results showed that women who took antimuscarinics for the treatment of overactive bladder were diagnosed with a higher incidence of depression of up to 38% than those who did not use antimuscarinics .

According to Li-Ting Kao of the Taiwan Medical University Hospital, the study again shows that the use of antimuscarinics for the treatment of overactive bladder is strongly associated with an increased risk of dyskinesia. cold in women.

This study has just been published in the Journal of Clinical Pharmacology.