That is why these patches have been developed.
When they are pressed on the body the letterad weighs for about two minutes, the microneedles (which are thinner than a human hair) will rupture and become embedded in the skin. They then dissolve harmlessly, slowly releasing the drug load directly into the required place - into the lower layer of white fat. The drugs then turn it into brown fat, which is the result when fat is burned.
In laboratory tests, the use of mouse patches with a high-fat diet reduced animal fat mass by over 30% in four weeks. They also significantly reduced blood cholesterol and fatty acid levels compared to the obese control group without the patch.
Professor Xu Chenjie said: "The number of drugs we use in the patch is much less than the current oral or weight-loss drug. This reduces drug costs, while the fat burning release design slows down. help minimize its side effects' .
This study is published in Small Methods journal.
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