Scientists identify target receptors for the treatment of glioblastoma
The researchers said they identified a type of receptor called protein-tyrosine Z phosphatase, or PTPRZ, as a drug target for patients with glioblastoma .
Glioblastoma has been classified by the World Health Organization as the highest level of fibroids, a type of brain tumor that is hard to cure with an average survival rate of only 14 months.
The lack of effective treatments for this disease has prompted researchers to look for other better treatments.
Researchers at the Institute of Basic Biology, or NIBB, have identified PTPRZ as an important factor to maintain the properties of stem cells and tumors in glioblastoma cells and by targeting PTPRZ, the Tumor growth can be strongly inhibited on glioblastoma C6 cells in mice.
The study also showed that the allosteric inhibitor of PTPRZ NAZ2329 could prevent stem cell-like properties in glioblastoma cells in culture and tumor growth in glioblastoma C6 cells.
Research published in the Journal of Scientific Reports shows that PTPRZ may be an important target for glioblastoma therapy.
You should read it
- Officially identified the target receptor for the treatment of neuroblastoma
- Children who survive a brain tumor have a very high body fat content
- Will Zika virus treat brain cancer?
- Researchers have figured out how breast cancer spreads to the brain
- Things you need to know about brain cancer
- First confirmation in the world: Having a brain tumor caused by using too many mobile phones
- How does daily activities affect the brain?
- You are often teased as the 'goldfish brain', do not be sad this indicates you have a brain that works very well
- Stem cells help patch brain damage in stroke victims
- How to download Brain Out on the computer, install Brain Out on the computer
- Interesting discovery: Human brain is more flexible than chimp brain
- Answers to Test Brain Level 1 to 60 (updated continuously)